A study In france had 25/36 pts had clearance. A Rash papulopustular sugests l ok nger disease free survival. IV infusion is done weekly for five sessions. Combining it With Radiation can also increase survival. This targeted molecular Therapy is the future.

Another nee molecular thrraph is for BCC tx using Erivedge (Vismodegib) a hedghog supresor is an antagonist Of smoothen receptor and this pathwy is found In 90prcnt Of bccs. It is taken daily by mouth untill tumor is cleared.

My notation: I have long recommended patients with allergies around the eyelids or around the nails to avoid nail polish and nail polish removers containing Toluene Sulfonamide Resin. The companies that fail to mention these carcinogenic ingredients are subject to reprimand, and the FDA has taken interest in enforcing their guidelines and prosecuting companies that fail to follow them.

This carcinogenicity is most likely of danger to those who are exposed all day in the salon, more than the clients who get their nails done, but the craze in having young girls getting nail polish should be curbed, and reputable companies should be used when searching for these carcinogenic ingredients in nail polish or nail polish removers.

2) The second is that summer is approaching and I see many patients coming to me to lighten their skin from freckles or melasma (aka the mask of pregnancy.) Many simply buy the bleaching creams on the Internet without the advice of a board certified dermatologist. The problem is that there have been recent evaluations of the bleaching creams available to consumers without prescriptions, and it was found that besides hydroquinone (which is now believed to be unsafe for long term use and may be stored in the body then passed to the growing fetus during a future pregnancy) some contain mercury which can lead to mercury poisoning.

The best thing is a good sunblock, but that too can contain carcinogenic ingredients as I have recently discovered. I currently only use zinc and titanium dioxide as physical blockers as opposed to any chemical sunscreens, but we will discuss the differences between chemical and physical sunblocking agents on another occasion.